Description

5-Fluoro-4-Mercapto-2-Hydroxypyrimidine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both mercapto and hydroxypyrimidine functionalities, makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, antiviral agents, and other biologically active pyrimidine derivatives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Chelating Agent: The mercapto and hydroxyl groups can act as coordination sites in metal-organic frameworks (MOFs) or catalytic systems.
• Material Science: Potential building block for functionalized polymers or organic electronic materials.

Basic Information

Product Name	5-Fluoro-4-Mercapto-2-Hydroxypyrimidine
CAS No.	671-41-0
Molecular Formula	C4H3FN2OS
Molecular Weight	146.14 g/mol
Synonyms	2-Hydroxy-5-fluoro-4-mercaptopyrimidine; 5-Fluoro-2-hydroxypyrimidine-4-thiol; 4-Mercapto-5-fluoro-2(1H)-pyrimidinone; 5-Fluoro-4-mercapto-2(1H)-pyrimidinone; 5-Fluoro-2-pyrimidinol-4-thione; 671-41-0; 5-Fluoro-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-Mercapto-2-Hydroxypyrimidine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage or when opening a new container. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.