Description

1-[2-(Trifluoromethyl)Phenyl]Propan-2-Amine is a specialized aromatic amine derivative featuring a trifluoromethyl substituent, a structural motif of significant interest in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the CF3 group is prized for its ability to modulate lipophilicity, metabolic stability, and binding affinity. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets and bioactive molecules requiring trifluoromethylated aromatic systems.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves compound efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis and other specialized organic transformations.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated aromatic components.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	1-[2-(Trifluoromethyl)Phenyl]Propan-2-Amine
CAS No.	670-04-2
Molecular Formula	C10H12F3N
Molecular Weight	203.21 g/mol
Synonyms	2-(Trifluoromethyl)amphetamine; α-Methyl[2-(trifluoromethyl)phenyl]methanamine; 1-[2-(Trifluoromethyl)phenyl]-2-propanamine; 2-(Trifluoromethyl)phenylisopropylamine; 2-TFMA; 2-Trifluoromethylamphetamine; 2-(α,α,α-Trifluoro-m-tolyl)isopropylamine; 1-(2-Trifluoromethylphenyl)-2-aminopropane
EINECS	Contact for details

Quality Control

Our 1-[2-(Trifluoromethyl)Phenyl]Propan-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.