Description

4(1H)-Pyrimidinone, 2-Amino-5-Fluoro-6-Hydroxy- (9Ci) is a high-purity, fluorinated pyrimidinone derivative, serving as a critical building block in advanced organic synthesis. Its unique heterocyclic structure, featuring amino and hydroxyl substituents, makes it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for the synthesis of complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of antiviral, anticancer, and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Biochemical Research: Serves as a precursor for labeled compounds and probes in metabolic and enzymatic studies.
• Material Science: A potential monomer or additive for creating specialty polymers with specific electronic or optical properties.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the fluorinated pyrimidinone core into target molecules.

Basic Information

Product Name	4(1H)-Pyrimidinone, 2-Amino-5-Fluoro-6-Hydroxy- (9Ci)
CAS No.	669-96-5
Molecular Formula	C4H4FN3O2
Molecular Weight	145.09 g/mol
Synonyms	2-Amino-5-fluoro-6-hydroxypyrimidin-4(1H)-one; 5-Fluoro-2-amino-6-hydroxy-4(1H)-pyrimidinone; 2-Amino-5-fluoro-6-hydroxy-4-pyrimidinol; 5-Fluoro-2,6-diamino-4(3H)-pyrimidinone (tautomer); 2-Amino-5-fluoro-6-hydroxy-4(3H)-pyrimidinone; 5-Fluoro-6-hydroxy-2,4-pyrimidinediamine; 669-96-5; FC-069
EINECS	Contact for details

Quality Control

Our production of 2-Amino-5-Fluoro-6-Hydroxy-4(1H)-Pyrimidinone adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.