Description

4-(Difluoromethoxy)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethoxy and benzyl alcohol functional groups, enabling precise molecular construction. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Functional Polymer Monomer: Employed to introduce aromatic and fluorinated segments into specialty polymers, modifying their thermal and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, etherifications, and esterifications to create complex, fluorinated molecular architectures.

Basic Information

Product Name	4-(Difluoromethoxy)Benzyl Alcohol
CAS No.	659-33-6
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	α-(Difluoromethoxy)-p-tolyl alcohol; (4-(Difluoromethoxy)phenyl)methanol; 1-[4-(Difluoromethoxy)phenyl]methanol; Benzyl alcohol, 4-(difluoromethoxy)-; p-(Difluoromethoxy)benzyl alcohol; 4-(Difluoromethoxymethyl)phenol (tautomer); DFMBA
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethoxy)Benzyl Alcohol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.