Description

1,2-Diamino-4-(Trifluoromethoxy)Benzene is a specialized aromatic diamine derivative featuring a trifluoromethoxy substituent, offering unique electronic and steric properties. This compound serves as a critical high-purity building block in advanced organic synthesis, where its dual amine functionality and fluorine content are essential for creating complex molecular architectures. It is primarily required by R&D and production chemists in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the trifluoromethoxy group.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine moiety enhances metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a chelating agent or backbone for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Acts as a monomer or cross-linking agent in the production of high-performance polyimides, polyamides, and other specialty polymers with enhanced thermal and chemical resistance.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex organic dyes and pigments, where the diamine structure is integral to chromophore development.
• Research & Development: A valuable reagent for academic and industrial research exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	1,2-Diamino-4-(Trifluoromethoxy)Benzene
CAS No.	658-89-9
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	4-(Trifluoromethoxy)-1,2-benzenediamine; 4-(Trifluoromethoxy)benzene-1,2-diamine; 1,2-Diamino-4-(trifluoromethoxy)benzene; 2-Amino-4-(trifluoromethoxy)aniline; 3,4-Diaminophenyl trifluoromethyl ether; 4-Trifluoromethoxy-o-phenylenediamine; OCF3-Aniline derivative; TFMOPD
EINECS	Contact for details

Quality Control

Our 1,2-Diamino-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP and ISO 9001 principles where applicable, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.