Description

A-Methyl-Dl-p-Tyrosine is a synthetic tyrosine derivative and a key intermediate in organic synthesis and pharmaceutical research. This compound is valued for its role as a precursor in the development of enzyme inhibitors and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, metabolic studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of enzyme inhibitors, particularly those targeting tyrosine hydroxylase and aromatic L-amino acid decarboxylase (AADC).
• Biochemical Research: Used as a substrate analog in studies of catecholamine biosynthesis and neurotransmitter regulation pathways.
• Neuroscience Research: Employed in experimental models to study Parkinson's disease, depression, and other neurological conditions by modulating dopamine and norepinephrine levels.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing laboratories.
• Organic Synthesis: Acts as a versatile chiral synthon for constructing more complex molecules with specific stereochemical configurations.

Basic Information

Product Name	A-Methyl-Dl-p-Tyrosine
CAS No.	658-48-0
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	α-Methyl-DL-tyrosine; DL-α-Methyl-p-tyrosine; DL-AMPT; Metirosine impurity; 3-(4-Hydroxyphenyl)-2-methylalanine; (±)-α-Methyl-4-hydroxybenzenealanine; H 44/68; NSC 113019
EINECS	211-517-3

Quality Control

Our A-Methyl-Dl-p-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Optical Purity (Chiral HPLC)	DL-mixture as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.