Description

4(1H)-Pyrimidinethione, 6-Methyl-2-(Trifluoromethyl)- is a high-purity heterocyclic building block characterized by its pyrimidine core functionalized with a thione and a trifluoromethyl group. This compound is valued for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily sought by research institutions and industrial manufacturers in the life sciences sector for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyrimidine scaffold.
• Chemical Research: Serves as a versatile building block in organic synthesis and medicinal chemistry for constructing complex heterocyclic systems.
• Material Science Precursor: Potential application in the development of specialty chemicals and functional materials.

Basic Information

Product Name	4(1H)-Pyrimidinethione, 6-Methyl-2-(Trifluoromethyl)-
CAS No.	657-50-1
Molecular Formula	C6H5F3N2S
Molecular Weight	194.18 g/mol
Synonyms	6-Methyl-2-(trifluoromethyl)-4(1H)-pyrimidinethione; 2-(Trifluoromethyl)-6-methyl-4-pyrimidinethiol; 4-Mercapto-6-methyl-2-(trifluoromethyl)pyrimidine; 6-Methyl-2-trifluoromethyl-4-pyrimidinol; 4-Hydroxy-6-methyl-2-(trifluoromethyl)pyrimidine; 4-Pyrimidinethiol, 6-methyl-2-(trifluoromethyl)-; NSC 403697
EINECS	Contact for details

Quality Control

Our 4(1H)-Pyrimidinethione, 6-Methyl-2-(Trifluoromethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.