Description

3-Fluoro-4-Iodoaniline is a halogenated aniline derivative serving as a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from halogenated aromatic structures.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing halogenated aromatic cores used in electronic display materials and organic light-emitting diodes.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Dye & Pigment Manufacturing: Intermediate for producing specialized azo dyes and pigments where halogen atoms modify color fastness and spectral properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	3-Fluoro-4-Iodoaniline
CAS No.	656-66-6
Molecular Formula	C6H5FIN
Molecular Weight	237.01 g/mol
Synonyms	4-Amino-2-fluoro-1-iodobenzene; 1-Iodo-2-fluoro-4-aminobenzene; 2-Fluoro-4-iodoaniline; 4-Iodo-3-fluoroaniline; Benzenamine, 3-fluoro-4-iodo-; 3-Fluoro-4-iodobenzenamine; 656-66-6; 3-Fluoro-4-iodo-phenylamine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Iodoaniline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.