Description

2,2-Difluorobenzodioxole-5-Carboxaldehyde is a high-purity fluorinated aromatic aldehyde building block, identified by CAS NO 656-42-8. This compound is valued for its unique difluorobenzodioxole scaffold, which imparts enhanced metabolic stability and lipophilicity to target molecules. It serves as a critical synthetic intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for improved bioactivity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, coatings, and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organic and medicinal chemistry for constructing complex molecular architectures and chiral ligands used in asymmetric catalysis.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new fluorinated heterocyclic compounds and their properties.

Basic Information

Product Name	2,2-Difluorobenzodioxole-5-Carboxaldehyde
CAS No.	656-42-8
Molecular Formula	C8H4F2O3
Molecular Weight	186.11 g/mol
Synonyms	5-Formyl-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-1,3-benzodioxole-5-carboxaldehyde; 2,2-Difluoro-1,3-benzodioxole-5-carbaldehyde; 656-42-8; Difluorobenzodioxole carboxaldehyde; Benzodioxole-5-carboxaldehyde, 2,2-difluoro-
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluorobenzodioxole-5-Carboxaldehyde is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.