Description

Ethyl 4-Amino-2-(Trifluoromethyl)Pyrimidine-5-Carboxylate is a high-value trifluoromethylated pyrimidine derivative, a key building block in modern synthetic chemistry. Its molecular structure, featuring both an amino group and a carboxylate ester, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Serves as a key synthon for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and development of specialty chemicals, dyes, and functional materials that require fluorinated pyrimidine cores.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, particularly in cross-coupling reactions and heterocycle formation.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to create diverse compound libraries for biological activity testing.

Basic Information

Product Name	Ethyl 4-Amino-2-(Trifluoromethyl)Pyrimidine-5-Carboxylate
CAS No.	653-95-2
Molecular Formula	C8H8F3N3O2
Molecular Weight	235.16 g/mol
Synonyms	Ethyl 4-Amino-2-(trifluoromethyl)-5-pyrimidinecarboxylate; 4-Amino-2-(trifluoromethyl)pyrimidine-5-carboxylic Acid Ethyl Ester; 5-Pyrimidinecarboxylic acid, 4-amino-2-(trifluoromethyl)-, ethyl ester; 2-(Trifluoromethyl)-4-aminopyrimidine-5-carboxylic Acid Ethyl Ester; Ethyl 4-Amino-2-trifluoromethylpyrimidine-5-carboxylate; 4-Amino-2-trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester; 653-95-2
EINECS	Contact for details

Quality Control

Our Ethyl 4-Amino-2-(Trifluoromethyl)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of this high-purity intermediate for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.