Description

2,3,5,6-Tetrafluoro-4-Aminobenzotrifluoride is a high-value fluorinated aromatic amine building block, distinguished by its unique trifluoromethyl and multiple fluorine substituents. This compound matters for its role in introducing lipophilicity, metabolic stability, and electron-withdrawing properties into advanced molecular architectures. It is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Imparts chemical resistance, thermal stability, and low surface energy properties to specialty polymers and coatings.
• Dye & Pigment Manufacturing: Employed in the synthesis of high-performance, light-fast fluorinated dyes and pigments.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-4-Aminobenzotrifluoride
CAS No.	651-83-2
Molecular Formula	C7H2F7N
Molecular Weight	245.09 g/mol
Synonyms	4-Amino-2,3,5,6-tetrafluorobenzotrifluoride; 2,3,5,6-Tetrafluoro-4-(trifluoromethyl)aniline; 4-Amino-α,α,α,2,3,5,6-heptafluorotoluene; Perfluoro-4-aminobenzotrifluoride; 4-(Trifluoromethyl)-2,3,5,6-tetrafluoroaniline; Heptafluoro-p-toluidine; 651-83-2; TFABTF
EINECS	211-477-4

Quality Control

Our 2,3,5,6-Tetrafluoro-4-Aminobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.