Description

16β-Acetoxy-3β-[(6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is a specialized cardiac glycoside derivative, a compound class known for its potent biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting cardiovascular conditions. It is primarily utilized by advanced research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathway for novel cardiac glycoside-based drugs.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of cardenolides and their interaction with sodium-potassium ATPase pumps.
• Academic Research: Serves as a substrate or reagent in university and institutional research exploring new therapeutic applications for cardiac glycosides.
• Process Development: Used in scaling up and optimizing synthetic routes for complex natural product derivatives in pilot plants.

Basic Information

Product Name	16β-Acetoxy-3β-[(6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No.	639-01-0
Molecular Formula	C32H48O11
Molecular Weight	608.72 g/mol
Synonyms	Acetyldigitoxin-α; 3β-[(6-Deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-14-hydroxy-16β-acetoxy-5β-card-20(22)-enolide; α-Acetyldigitoxin; Digitoxin 16-acetate; 16β-Acetoxy-3β-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; Acetyldigoxin impurity; Cardiac glycoside derivative
EINECS	Contact for details

Quality Control

Our 16β-Acetoxy-3β-[(6-Deoxy-3-o-Methyl-α-L-Mannopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.