Description

S-(1,2-Dichlorovinyl)Cysteine is a specialized organosulfur compound of significant interest in biochemical and toxicological research. This compound serves as a critical reference standard and metabolite in studies investigating the nephrotoxic effects of halogenated hydrocarbons. It is primarily utilized by researchers and analytical laboratories in the fields of toxicology, environmental science, and pharmaceutical development for mechanistic studies and analytical method validation.

Application

• Biochemical Research: Used as a key metabolite in studying the bioactivation pathways and nephrotoxicity of chlorinated solvents like trichloroethylene.
• Analytical Reference Standard: Serves as a high-purity standard for calibrating instruments (HPLC, LC-MS) in environmental and biological monitoring.
• Toxicology Studies: Employed in in vitro and in vivo models to understand renal proximal tubule cell injury mechanisms.
• Metabolite Synthesis: Acts as a synthetic intermediate or precursor for the preparation of other cysteine-conjugated metabolites.
• Method Development: Critical for developing and validating sensitive analytical methods to detect cysteine conjugates in complex matrices.

Basic Information

Product Name	S-(1,2-Dichlorovinyl)Cysteine
CAS No.	627-72-5
Molecular Formula	C5H7Cl2NO2S
Molecular Weight	228.09 g/mol
Synonyms	DCVC; S-(1,2-Dichloroethenyl)-L-cysteine; (2R)-2-Amino-3-[(1,2-dichloroethenyl)sulfanyl]propanoic acid; L-Cysteine, S-(1,2-dichlorovinyl)-; NSC 87431; Trichloroethylene Cysteine Conjugate; S-(1,2-Dichloroethenyl)cysteine
EINECS	210-979-5

Quality Control

Every batch of S-(1,2-Dichlorovinyl)Cysteine is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific batch results for purity, identity (IR, NMR), and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity, the material should be handled under an inert atmosphere when appropriate and protected from prolonged exposure to air to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.