Description

3-Hydroxybutyric Acid is a key short-chain hydroxy acid and a primary ketone body, serving as a crucial metabolic intermediate in both mammalian and microbial systems. Its significance lies in its role as a versatile chiral building block for synthesizing fine chemicals, pharmaceuticals, and biodegradable polymers. This compound is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries, particularly for developing β-hydroxy acid derivatives and studying energy metabolism.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of statin drugs, antibiotics, and other active pharmaceutical ingredients (APIs) requiring chiral β-hydroxy acid structures.
• Biodegradable Polymer Synthesis: Serves as a monomer or co-monomer for producing polyhydroxyalkanoates (PHAs), a family of biocompatible and biodegradable plastics.
• Biochemical Research: Used as a standard or substrate in metabolic studies, particularly related to ketosis, starvation, diabetes, and energy homeostasis.
• Nutraceutical & Cosmetic Formulations: Investigated for potential applications in dietary supplements for energy metabolism and in skincare for its moisturizing and exfoliating properties as a β-hydroxy acid (BHA).
• Chiral Synthesis: Employed as a chiral pool starting material or resolving agent for the asymmetric synthesis of complex organic molecules.
• Microbial Fermentation Studies: Acts as a carbon source or metabolic product in industrial microbiology and bioprocess development.

Basic Information

Product Name	3-Hydroxybutyric Acid
CAS No.	625-71-8
Molecular Formula	C4H8O3
Molecular Weight	104.10 g/mol
Synonyms	3-Hydroxybutanoic Acid; β-Hydroxybutyric Acid; BHBA; (R/S)-3-Hydroxybutyric Acid; DL-3-Hydroxybutyric Acid; 3-Hydroxybutyrate; β-Hydroxybutyric Acid; BHB Acid
EINECS	210-892-1

Quality Control

Our 3-Hydroxybutyric Acid is produced and tested under a strict quality management system. We offer various grades, including high-purity grades suitable for pharmaceutical research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures compliance with relevant standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions if specified. For long-term storage of certain high-purity grades, refrigeration (2-8°C) under an inert atmosphere may be recommended.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or white crystalline solid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Specify (R)-, (S)-, or Racemic
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.