Description

Dl-Proline CAS NO 609-36-9 is a non-essential amino acid derivative, serving as the racemic mixture of the D- and L- isomers of proline. This compound is a versatile chiral building block and intermediate of significant importance in organic synthesis and pharmaceutical research. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers for applications ranging from asymmetric catalysis to the synthesis of complex bioactive molecules and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in protease inhibitors and other bioactive peptides.
• Asymmetric Synthesis: Used as a ligand or catalyst component in enantioselective reactions to produce optically active compounds.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway analysis, and as a component in cell culture media for specialized applications.
• Peptide Chemistry: Acts as a building block for the solid-phase and solution-phase synthesis of custom peptides and peptidomimetics.
• Cosmetic & Personal Care: Incorporated into formulations for its potential skin-conditioning and moisturizing properties.
• Food & Nutrition: Used in research related to flavor enhancers and nutritional supplements.

Basic Information

Product Name	Dl-Proline
CAS No.	609-36-9
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	DL-Proline; (±)-Proline; Racemic Proline; 2-Pyrrolidinecarboxylic Acid, DL-; Proline, DL-; NSC 83688; DL-2-Carboxypyrrolidine; (±)-2-Pyrrolidinecarboxylic Acid
EINECS	210-189-3

Quality Control

Our Dl-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications including assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation	± 0.5° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.