Description

2,4-Dichloroquinazoline CAS NO 607-68-1 is a versatile halogenated heterocyclic building block of significant importance in synthetic organic chemistry. Its high reactivity, particularly at the 2- and 4-positions, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various biologically active quinazoline derivatives, including kinase inhibitors, anticancer agents, and antimicrobial compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the quinazoline scaffold's bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and functional polymers.
• Dye and Pigment Chemistry: Intermediate for the production of specialized quinazoline-based dyes and fluorescent markers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up processes.

Basic Information

Product Name	2,4-Dichloroquinazoline
CAS No.	607-68-1
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	2,4-Dichloro-quinazoline; Quinazoline, 2,4-dichloro-; 2,4-DCQ; 607-68-1; NSC 51128; 2,4-Dichlorbenzo[d]pyrimidine
EINECS	210-142-8

Quality Control

Our 2,4-Dichloroquinazoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under a dry inert atmosphere for long-term storage and to minimize exposure to humid air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.