Description

Eledoisin CAS NO 69-25-0 is a bioactive undecapeptide originally isolated from the posterior salivary glands of the mollusk *Eledone moschata*. This compound is a potent and selective agonist for the neurokinin NK2 receptor, making it a critical research tool in neuropharmacology and physiology. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on studying smooth muscle contraction, vasodilation, and pain signaling pathways.

Application

• Pharmacological Research: As a standard NK2 receptor agonist for studying receptor binding, activation, and downstream signaling cascades in vitro and in vivo.
• Smooth Muscle Physiology Studies: Investigation of its potent contractile effects on various smooth muscle tissues, including those from the gastrointestinal tract, urinary bladder, and respiratory system.
• Vascular Research: Examination of its vasodilatory and hypotensive effects, contributing to studies on blood pressure regulation and cardiovascular function.
• Neuroscience & Pain Research: Used in models to explore the role of tachykinin peptides and NK2 receptors in nociception (pain perception) and neurogenic inflammation.
• Biochemical Standard: Serves as a high-purity reference standard for analytical method development, validation, and quality control in peptide analysis.
• Drug Discovery: A key compound for screening and developing novel antagonists or modulators of the NK2 receptor for potential therapeutic applications.

Basic Information

Product Name	Eledoisin
CAS No.	69-25-0
Molecular Formula	C₅₄H₈₅N₁₅O₁₅S
Molecular Weight	1188.4 g/mol
Synonyms	Eledoisin; Eledoisin Peptide; pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH₂; (Pyroglutamyl-Prolyl-Seryl-Lysyl-Aspartyl-Alanyl-Phenylalanyl-Isoleucyl-Glycyl-Leucyl-Methioninamide); Molluscan Peptide; NK2 Receptor Agonist
EINECS	Contact for details

Quality Control

Our Eledoisin is manufactured under strict quality management systems to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for peptide synthesis and can provide material traceable to primary reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.