Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphocholine (DPPC) is a synthetic, high-purity phospholipid that serves as a critical building block in advanced formulation science. Its primary value lies in its ability to form stable, well-defined lamellar structures, making it indispensable for creating controlled and reproducible lipid-based systems. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material sectors who require a reliable and consistent excipient for liposomal drug delivery, membrane model studies, and pulmonary surfactant applications.

Application

• Liposomal Drug Delivery Systems: A primary component for formulating stable, long-circulating liposomes to encapsulate and deliver therapeutic agents.
• Pulmonary Surfactant Mimetics: Used in research and development of synthetic lung surfactants for treating respiratory distress syndrome.
• Biomembrane Model Studies: Essential for creating defined lipid bilayers (e.g., vesicles, supported bilayers) to study membrane biophysics, protein-lipid interactions, and permeability.
• Biocompatible Coatings & Materials: Employed in the surface functionalization of medical devices and nanoparticles to enhance biocompatibility and reduce immune recognition.
• Cosmetic & Dermal Formulations: Acts as a high-performance emollient and stabilizer in premium skincare products designed for enhanced skin barrier repair and moisturization.
• Diagnostic Reagent Preparation: Used in the formulation of lipid-based reagents for various diagnostic assays and imaging techniques.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phosphocholine
CAS No.	63-89-8
Molecular Formula	C40H80NO8P
Molecular Weight	734.04 g/mol
Synonyms	DPPC; 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine; L-α-Phosphatidylcholine, dipalmitoyl; Dipalmitoyl phosphatidylcholine; Dipalmitoyl lecithin; 1,2-Dipalmitoylphosphatidylcholine; PC(16:0/16:0); (2R)-2,3-Bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
EINECS	200-567-0

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, TLC for lipid profiling, and NMR for structural confirmation, to ensure it meets stringent specifications for research and GMP-guided applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and hydrolysis. Under these conditions, the product is typically stable for at least two years. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Approx. 41 - 46 °C
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 10 ppm
Solvents (Residual)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.