Description

1H-Indazole-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative of the indazole heterocycle. This compound serves as a critical building block in organic synthesis, enabling the introduction of the indazole-5-sulfonyl moiety into target molecules. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by acting as a sulfonating agent.
• Chemical Biology Probe Synthesis: Employed to create sulfonamide-linked probes for studying protein function and enzyme activity.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates for client projects.

Basic Information

Product Name	1H-Indazole-5-Sulfonyl Chloride
CAS No.	599183-35-4
Molecular Formula	C7H5ClN2O2S
Molecular Weight	216.64 g/mol
Synonyms	1H-Indazole-5-sulfonyl chloride; 5-Indazolesulfonyl chloride; Indazole-5-sulfonyl chloride; 1H-Indazole-5-sulfonchlorid; 599183-35-4; 5-Sulfonyl chloride indazole; 1H-Indazol-5-ylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Indazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.