Description

4-Chloro-2-(Methylsulfonyl)Thieno[2,3-D]Pyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique fused-ring structure, featuring both pyrimidine and thiophene moieties, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for organic electronic materials and functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biological studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	4-Chloro-2-(Methylsulfonyl)Thieno[2,3-D]Pyrimidine
CAS No.	598298-11-4
Molecular Formula	C7H5ClN2O2S2
Molecular Weight	248.71 g/mol
Synonyms	4-Chloro-2-(methylsulfonyl)thieno[2,3-d]pyrimidine; 4-Chloro-2-methanesulfonylthieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 4-chloro-2-(methylsulfonyl)-; 2-(Methylsulfonyl)-4-chlorothieno[2,3-d]pyrimidine; 4-Chloro-2-methylsulfonyl-thieno[2,3-d]pyrimidine; CAS 598298-11-4
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(Methylsulfonyl)Thieno[2,3-D]Pyrimidine adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for cGMP and non-GMP pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.