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Antibacterial Protein Ll-37 Amide (Human) CAS NO 597562-32-8
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CAS No.:597562-32-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Antibacterial Protein Ll-37 Amide (Human) is a synthetic, amidated form of the human cathelicidin-derived antimicrobial peptide LL-37. This compound is of significant interest for its broad-spectrum antimicrobial, immunomodulatory, and wound-healing properties. It is primarily utilized in advanced biomedical research, pharmaceutical development, and the formulation of novel antimicrobial and anti-inflammatory therapeutic agents.
Application
- Biomedical Research: Fundamental studies on innate immunity, host defense mechanisms, and peptide structure-activity relationships.
- Pharmaceutical Development: As a lead compound or active pharmaceutical ingredient (API) in the development of novel anti-infective and immunomodulatory drugs.
- Wound Healing & Dermatology: Research and formulation of topical treatments for chronic wounds, burns, and skin infections due to its antimicrobial and tissue-regenerative effects.
- Antimicrobial Coatings: Investigation for incorporation into medical device coatings, biomaterials, and textiles to prevent biofilm formation and microbial colonization.
- Cosmeceutical Research: Exploration in high-end skincare formulations targeting inflammation and promoting skin barrier function.
- Veterinary Medicine: Development of therapeutic alternatives to traditional antibiotics for animal health.
Basic Information
| Product Name | Antibacterial Protein Ll-37 Amide (Human) |
| CAS No. | 597562-32-8 |
| Molecular Formula | C₂₀₄H₃₄₀N₆₀O₅₃S |
| Molecular Weight | 4493.0 g/mol (approximate) |
| Synonyms | LL-37 amide (human); hCAP-18 (LL-37) amide; Cathelicidin antimicrobial peptide LL-37 amide; FALL-39 amide; CAMP (LL-37) amide; Antimicrobial peptide LL37 amide; Leu-Leu-37 amide |
| EINECS | Contact for details |
Quality Control
Our Antibacterial Protein Ll-37 Amide (Human) is produced and controlled under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, peptide content, and endotoxin levels are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 80% (by weight) |
| Molecular Weight | 4493.0 ± 2.0 Da (MALDI-TOF MS) |
| Water Content (KF) | ≤ 5.0% |
| Endotoxin Level | < 10 EU/mg |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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