Description

2-Chloro-n-(1-Phenylethyl)Quinazolin-4-Amine is a specialized quinazoline derivative, a key chemical scaffold in medicinal chemistry and advanced material science. This compound matters as a versatile and high-purity building block for the synthesis of novel pharmacologically active molecules, particularly in oncology and kinase inhibitor research. Pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers need this precise intermediate to accelerate their discovery pipelines and develop next-generation products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors and other small-molecule therapeutic candidates.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in research for creating novel crop protection agents and pesticides.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic compounds in academic and industrial research.
• Material Science Research: Investigated as a potential component in the development of organic electronic materials.

Basic Information

Product Name	2-Chloro-n-(1-Phenylethyl)Quinazolin-4-Amine
CAS No.	597545-50-1
Molecular Formula	C₁₆H₁₄ClN₃
Molecular Weight	283.76 g/mol
Synonyms	4-Amino-2-chloro-N-(1-phenylethyl)quinazoline; 2-Chloro-N-(α-methylbenzyl)quinazolin-4-amine; 2-Chloro-N-(1-phenylethyl)-4-quinazolinamine; Quinazolin-4-amine, 2-chloro-N-(1-phenylethyl)-; N-(1-Phenylethyl)-2-chloroquinazolin-4-amine; 2-Chloro-N-(α-methylbenzyl)quinazolin-4-amine; 2-Chloro-4-((1-phenylethyl)amino)quinazoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(1-Phenylethyl)Quinazolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.