Description

2-Fluoro-4-(Trifluoromethylthio)Aniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethylthio group, makes it an essential intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This product is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and sulfur-containing moiety can improve efficacy and environmental profile.
• Material Science Research: Building block for novel polymers, liquid crystals, and electronic materials that require specific dielectric properties or chemical resistance.
• Dye and Pigment Chemistry: Intermediate for synthesizing specialized dyes and pigments with unique color fastness and stability properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for constructing complex aromatic amines.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethylthio)Aniline
CAS No.	596850-17-8
Molecular Formula	C7H5F4NS
Molecular Weight	211.18 g/mol
Synonyms	2-Fluoro-4-(trifluoromethylsulfanyl)aniline; 4-Amino-3-fluoro-1-(trifluoromethylthio)benzene; 2-Fluoro-4-(trifluoromethylthio)benzenamine; 2-Fluoro-4-(trifluoromethylmercapto)aniline; 2-Fluoro-4-(trifluoromethylsulfanyl)benzenamine; 2-Fluoro-4-(trifluoromethylthio)phenylamine; 2-Fluoro-4-(trifluoromethylthio)aminobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethylthio)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.