Description

1-(4-Chloro-Pyrimidin-2-Yl)-4-Piperidinamine is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, featuring a reactive chloro-pyrimidine group and a piperidinamine moiety, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Chemical Biology: Serves as a valuable probe or linker in the design of chemical tools for studying biological pathways.
• Material Science: Potential precursor for the synthesis of specialty polymers or ligands for catalytic systems.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex piperidine-pyrimidine hybrids.

Basic Information

Product Name	1-(4-Chloro-Pyrimidin-2-Yl)-4-Piperidinamine
CAS No.	596818-00-7
Molecular Formula	C9H12ClN5
Molecular Weight	225.68 g/mol
Synonyms	4-Piperidinamine, 1-(4-chloro-2-pyrimidinyl)-; 1-(4-Chloro-2-pyrimidinyl)-4-piperidinamine; 4-Amino-1-(4-chloropyrimidin-2-yl)piperidine; 2-(4-Aminopiperidin-1-yl)-4-chloropyrimidine; 4-Chloro-2-(4-aminopiperidin-1-yl)pyrimidine; 1-(4-Chloropyrimidin-2-yl)piperidin-4-amine; N-(4-Chloro-2-pyrimidinyl)-4-piperidinamine
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Pyrimidin-2-Yl)-4-Piperidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.