Description

[1-(2-Chloro-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition. It is essential for research and production teams in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for scalable synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Synthesis: Employed in the commercial-scale production of active pharmaceutical ingredients for oncology and other therapeutic areas.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom chemical synthesis services catering to pharmaceutical clients.
• Biochemical Tool Compound Development: Utilized in the creation of specialized probes and inhibitors for biological pathway analysis.

Basic Information

Product Name	[1-(2-Chloro-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	596817-49-1
Molecular Formula	C14H19ClN4O2
Molecular Weight	310.78 g/mol
Synonyms	tert-Butyl N-[1-(2-chloropyrimidin-4-yl)piperidin-4-yl]carbamate; 1-(2-Chloro-4-pyrimidinyl)-4-[(1,1-dimethylethoxy)carbonylamino]piperidine; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(2-chloro-4-pyrimidinyl)piperidine; BOC-Piperidine-Pyrimidine Chloride Intermediate; 596817-49-1; 1-(2-Chloropyrimidin-4-yl)piperidin-4-amine, N-BOC-protected
EINECS	Contact for details

Quality Control

Our production of [1-(2-Chloro-Pyrimidin-4-Yl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.