Description

D-Cys,A-Msh CAS NO 596135-92-1 is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH), modified with a D-cysteine residue to enhance its metabolic stability and receptor binding profile. This modification is critical for research and development in advanced therapeutic areas, offering superior performance compared to native sequences. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, dermatology, and inflammation-related drug discovery.

Application

• Biomedical Research: Used as a key reference standard and active agent in studies of melanocortin receptor (MCR) signaling pathways.
• Drug Discovery: Serves as a lead compound or intermediate in the development of novel therapeutics for skin pigmentation disorders, inflammatory conditions, and metabolic diseases.
• Pharmacology Studies: Employed in in vitro and in vivo assays to investigate anti-inflammatory and immunomodulatory effects.
• Peptide Chemistry: Acts as a building block or model compound for studying structure-activity relationships (SAR) and peptide stability.
• Diagnostic Development: Potential use in the formulation of diagnostic kits or tools targeting the melanocortin system.

Basic Information

Product Name	D-Cys,A-Msh
CAS No.	596135-92-1
Molecular Formula	C₇₇H₁₁₁N₂₁O₁₉S
Molecular Weight	1647.9 g/mol
Synonyms	[D-Cys⁴]-α-MSH; D-Cys⁴-α-Melanocyte Stimulating Hormone; α-MSH (D-Cys⁴) analog; Melanotropin (4-D-cysteine) analog; Ac-Ser-Tyr-Ser-D-Cys-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂; N-Acetyl-[D-Cys⁴]-α-MSH; [D-Cys⁴]-α-Melanotropin
EINECS	Contact for details

Quality Control

Our D-Cys,A-Msh is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant use and storage under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.