Description

Benzamide, 3,5-Bis(1,1-Dimethylethyl)-N-[1-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-3-Methyl-6-(Methylamino)-2,4-Dioxo-5-Pyrimidinyl]-4-Hydroxy- is a high-purity, complex heterocyclic organic compound designed for advanced research and development applications. This specialized chemical serves as a critical building block or intermediate in the synthesis of novel pharmaceutical candidates, particularly those targeting specific enzymatic pathways. It is essential for medicinal chemistry researchers and process development scientists in the pharmaceutical and biotechnology sectors who require reliable access to structurally defined, high-quality intermediates to accelerate their discovery pipelines.

Application

This compound is utilized in sophisticated chemical synthesis and research environments. Key application areas include:

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Tool Compound: Potential use in vitro as a probe to study specific biological targets and mechanisms of action.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for potential drug candidates during late-stage R&D.

Basic Information

Product Name	Benzamide, 3,5-Bis(1,1-Dimethylethyl)-N-[1-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-3-Methyl-6-(Methylamino)-2,4-Dioxo-5-Pyrimidinyl]-4-Hydroxy-
CAS No.	595558-86-4
Molecular Formula	C31H40FN5O4
Molecular Weight	565.68 g/mol
Synonyms	4-Hydroxy-3,5-di-tert-butyl-N-[1-(4-fluorophenyl)-3-methyl-6-(methylamino)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl]benzamide; 3,5-Di-tert-butyl-4-hydroxy-N-[1-(4-fluorophenyl)-3-methyl-6-(methylamino)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl]benzamide; Benzamide, 3,5-bis(1,1-dimethylethyl)-N-[1-(4-fluorophenyl)-1,2,3,4-tetrahydro-3-methyl-6-(methylamino)-2,4-dioxo-5-pyrimidinyl]-4-hydroxy-; 595558-86-4; 4-Hydroxy-3,5-di-tert-butylbenzoic acid [1-(4-fluorophenyl)-3-methyl-6-(methylamino)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl]amide
EINECS	Contact for details

Quality Control

Our Benzamide, 3,5-Bis(1,1-Dimethylethyl)-N-[1-(4-Fluorophenyl)-1,2,3,4-Tetrahydro-3-Methyl-6-(Methylamino)-2,4-Dioxo-5-Pyrimidinyl]-4-Hydroxy- is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handle and store under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.