Description

Imidazo[1,2-C]Pyrimidine-7-Carboxamide, n-(1R,3R,4S)-1- is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for the research and development of novel pharmaceutical agents, particularly in the areas of kinase inhibitors and other targeted therapies. It is primarily needed by medicinal chemists and process development scientists in pharmaceutical R&D, biotechnology, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A critical chiral scaffold for the synthesis of investigational drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core structural component in the design and synthesis of potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry & Scale-Up: Employed in the development of robust, scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Biochemical Probe Synthesis: Utilized to create tool compounds for studying specific biological targets and mechanisms of action.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity chiral building blocks.

Basic Information

Product Name	Imidazo[1,2-C]Pyrimidine-7-Carboxamide, n-(1R,3R,4S)-1-
CAS No.	588722-57-0
Molecular Formula	C8H9N5O
Molecular Weight	191.19 g/mol
Synonyms	(1R,3R,4S)-N-(1-Amino-3-hydroxycyclopentyl)imidazo[1,2-c]pyrimidine-7-carboxamide; (1R,3R,4S)-1-Amino-3-hydroxycyclopentanecarboxamide derivative; Imidazo[1,2-c]pyrimidine-7-carboxylic acid, N-[(1R,3R,4S)-1-amino-3-hydroxycyclopentyl]-; Chiral Imidazopyrimidine Carboxamide; 588722-57-0; Building Block 588722-57-0; (1R,3R,4S)-Isomer of Imidazopyrimidine Carboxamide
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-C]Pyrimidine-7-Carboxamide, n-(1R,3R,4S)-1- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity, suitable for demanding research and development applications. We provide comprehensive analytical data including HPLC purity, chiral purity, and identity confirmation. Certificates of Analysis (COA) with detailed specifications are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.