Description

Ethyl 6-Bromoh-Pyrrolo[1,2-F]Pyrimidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyrrolopyrimidine core structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on oncology, antiviral, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex heterocyclic systems.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Agrochemical Research: Potential intermediate for developing new crop protection agents with novel modes of action.

Basic Information

Product Name	Ethyl 6-Bromoh-Pyrrolo[1,2-F]Pyrimidine-3-Carboxylate
CAS No.	588720-12-1
Molecular Formula	C9H8BrN3O2
Molecular Weight	270.08 g/mol
Synonyms	Ethyl 6-Bromo-1H-pyrrolo[1,2-f]pyrimidine-3-carboxylate; 6-Bromo-1H-pyrrolo[1,2-f]pyrimidine-3-carboxylic acid ethyl ester; 1H-Pyrrolo[1,2-f]pyrimidine-3-carboxylic acid, 6-bromo-, ethyl ester; Ethyl 6-bromopyrrolo[1,2-f]pyrimidine-3-carboxylate; 588720-12-1; 6-Bromopyrrolo[1,2-f]pyrimidine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromoh-Pyrrolo[1,2-F]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.