Description

9-(4-Ethoxyphenyl)-6,6-Dimethyl-5,6,7,9-Tetrahydro[1,2,4]Triazolo[5,1-B]Quinazolin-8(4H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic quinazolinone class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly for central nervous system (CNS) and oncology applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of proprietary drug candidates, particularly those targeting neurological pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of potential APIs, especially within the triazolquinazolinone pharmacophore class.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	9-(4-Ethoxyphenyl)-6,6-Dimethyl-5,6,7,9-Tetrahydro[1,2,4]Triazolo[5,1-B]Quinazolin-8(4H)-One
CAS No.	587008-19-3
Molecular Formula	C21H24N4O2
Molecular Weight	364.45 g/mol
Synonyms	9-(4-Ethoxyphenyl)-6,6-dimethyl-4,5,6,7,8,9-hexahydro-[1,2,4]triazolo[5,1-b]quinazolin-8-one; 6,6-Dimethyl-9-(4-ethoxyphenyl)-5,6,7,9-tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one; 587008-19-3; UNII-7V6S3Q1Q5I; SCHEMBL218062; BCP31833; AOB81117; ZINC000644098535
EINECS	Contact for details

Quality Control

Our 9-(4-Ethoxyphenyl)-6,6-Dimethyl-5,6,7,9-Tetrahydro[1,2,4]Triazolo[5,1-B]Quinazolin-8(4H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets stringent specifications for pharmaceutical R&D use. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.