Description

5-(Chloromethyl)-2-(Methylthio)Pyrimidine is a versatile and high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive chloromethyl group and a methylthio substituent, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical, agrochemical, and specialty chemical research and development teams for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.

Basic Information

Product Name	5-(Chloromethyl)-2-(Methylthio)Pyrimidine
CAS No.	586382-17-4
Molecular Formula	C6H7ClN2S
Molecular Weight	174.65 g/mol
Synonyms	2-(Methylthio)-5-(chloromethyl)pyrimidine; 5-(Chloromethyl)-2-methylsulfanylpyrimidine; 2-Methylsulfanyl-5-chloromethylpyrimidine; Pyrimidine, 5-(chloromethyl)-2-(methylthio)-; 586382-17-4
EINECS	Contact for details

Quality Control

Every batch of 5-(Chloromethyl)-2-(Methylthio)Pyrimidine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and other relevant tests, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.