Description

2,4-Difluoro-6-Iodoaniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as drug discovery and functional material design.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the difluoro and iodo groups contribute to biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and cross-coupling reactions (e.g., Buchwald-Hartwig amination).
• Functional Material Precursor: Employed in the research and production of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Fluorinated Compound Library: A valuable scaffold for medicinal chemistry to build diverse compound libraries for high-throughput screening in drug discovery programs.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new synthetic methodologies involving halogenated aromatic amines.

Basic Information

Product Name	2,4-Difluoro-6-Iodoaniline
CAS No.	582319-15-1
Molecular Formula	C6H4F2IN
Molecular Weight	254.99 g/mol
Synonyms	6-Iodo-2,4-difluoroaniline; 2,4-Difluoro-6-iodobenzenamine; 1-Amino-2,4-difluoro-6-iodobenzene; 2,4-Difluoro-6-iodophenylamine; Benzenamine, 2,4-difluoro-6-iodo-; 6-Iodo-2,4-difluorophenylamine; 2,4-Difluoro-6-iodoaniline (primary name)
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-6-Iodoaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive and should be handled under an inert atmosphere when appropriate to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.