Description

4-Chloro-5-Fluoro-7H-Pyrrolo[2,3-D]-Pyrimidine is a high-value, halogenated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical synthetic intermediate, enabling the construction of complex molecular architectures with targeted biological activity. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a versatile scaffold for probing enzyme active sites and designing chemical probes.
• Material Science: Potential precursor for the synthesis of organic electronic materials and ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization.
• Academic Research: Used in university and institutional labs for methodological development and discovery chemistry.

Basic Information

Product Name	4-Chloro-5-Fluoro-7H-Pyrrolo[2,3-D]-Pyrimidine
CAS No.	582313-57-3
Molecular Formula	C6H3ClFN3
Molecular Weight	171.56 g/mol
Synonyms	4-Chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-fluoro-; 4-Chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine; 582313-57-3; 4-Chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine (CAS 582313-57-3); 4-Chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine, 95+%; 4-Chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine, 98%
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-7H-Pyrrolo[2,3-D]-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes ensures reliable supply for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.