Description

3-(6-Chloropyrimidin-4-Yl)Benzoic Acid is a high-purity organic intermediate featuring a benzoic acid moiety linked to a chloropyrimidine ring. This specific molecular architecture makes it a valuable building block for synthesizing more complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector. The compound's structure offers versatile sites for further functionalization, enabling the creation of targeted bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators where the pyrimidine core is a common bioactive motif.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers and liquid crystals.
• Chemical Biology: Employed as a molecular probe or linker in proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules.
• Academic & Contract Research: Utilized in university and CRO laboratories for exploratory synthetic chemistry and medicinal chemistry programs.

Basic Information

Product Name	3-(6-Chloropyrimidin-4-Yl)Benzoic Acid
CAS No.	579476-50-9
Molecular Formula	C11H7ClN2O2
Molecular Weight	234.64 g/mol
Synonyms	3-(6-Chloro-4-pyrimidinyl)benzoic acid; 4-(3-Carboxyphenyl)-6-chloropyrimidine; Benzoic acid, 3-(6-chloro-4-pyrimidinyl)-; 6-Chloro-4-(3-carboxyphenyl)pyrimidine; 3-(6-Chloropyrimidin-4-yl)benzoic acid; 579476-50-9; 3-(6-Chloro-pyrimidin-4-yl)-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(6-Chloropyrimidin-4-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP-compliant production for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.