Description

N,n-Dimethyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyridopyrimidine class of heterocyclic compounds. Its molecular architecture makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and the pilot-scale manufacturing of candidate drugs.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays to study specific enzyme or receptor interactions.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials.

Basic Information

Product Name	N,n-Dimethyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-2-Amine
CAS No.	578713-43-6
Molecular Formula	C11H16N4
Molecular Weight	204.27 g/mol
Synonyms	2-(Dimethylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; N,N-Dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine; 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidin-2-amine, N,N-dimethyl-; Tetrahydropyridopyrimidine derivative
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications from early-stage research to cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.