Description

1-(6-{[(4-Chlorophenyl)Sulfanyl]Methyl}-4-Oxo-1,4-Dihydropyrimidin-2-Yl)-3-Phenylguanidine CAS NO 577987-90-7 is a high-purity, complex heterocyclic organic compound featuring a pyrimidinone core functionalized with chlorophenylthio and phenylguanidine groups. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in academic and industrial R&D settings.
• Biochemical Probe Development: Employed in the design and creation of molecular probes for studying biological pathways and target validation.
• Fine Chemical Synthesis: Acts as a key building block for the multi-step synthesis of complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Item	Details
Product Name	1-(6-{[(4-Chlorophenyl)Sulfanyl]Methyl}-4-Oxo-1,4-Dihydropyrimidin-2-Yl)-3-Phenylguanidine
CAS No.	577987-90-7
Molecular Formula	C18H16ClN5OS
Molecular Weight	385.87 g/mol
Synonyms	1-(6-(((4-Chlorophenyl)thio)methyl)-4-oxo-1,4-dihydropyrimidin-2-yl)-3-phenylguanidine; 3-Phenyl-1-[6-[(4-chlorophenyl)sulfanylmethyl]-4-oxo-1H-pyrimidin-2-yl]guanidine; 1-(6-{[(4-Chlorophenyl)thio]methyl}-4-oxo-1,4-dihydro-2-pyrimidinyl)-3-phenylguanidine; 2-(N'-Phenylcarbamimidamido)-6-((4-chlorophenylthio)methyl)pyrimidin-4(1H)-one; CAS 577987-90-7
EINECS	Contact for details

Quality Control

Our production of 1-(6-{[(4-Chlorophenyl)Sulfanyl]Methyl}-4-Oxo-1,4-Dihydropyrimidin-2-Yl)-3-Phenylguanidine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.