Description

N⁴-(3-Chlorophenyl)-N²-(4-Methylbenzyl)-5-Nitropyrimidine-2,4,6-Triamine is a high-purity, advanced pharmaceutical intermediate belonging to the nitropyrimidine class of heterocyclic compounds. Its precise molecular architecture makes it a critical building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for innovative drug discovery and manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially in oncology and antiviral research.
• Chemical Research & Development: Used as a specialized reagent for constructing complex pyrimidine-based molecular scaffolds in academic and industrial R&D laboratories.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral in the production pathway for target APIs where the nitropyrimidine core is a required pharmacophore.
• Process Chemistry & Scale-Up: Employed in optimizing and scaling synthetic routes from milligram to kilogram scale for clinical trial material production.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing.

Basic Information

Product Name	N⁴-(3-Chlorophenyl)-N²-(4-Methylbenzyl)-5-Nitropyrimidine-2,4,6-Triamine
CAS No.	577790-39-7
Molecular Formula	C₁₈H₁₇ClN₆O₂
Molecular Weight	384.82 g/mol
Synonyms	5-Nitro-N4-(3-chlorophenyl)-N2-[(4-methylphenyl)methyl]-2,4,6-pyrimidinetriamine; 2,4,6-Pyrimidinetriamine, N4-(3-chlorophenyl)-5-nitro-N2-[(4-methylphenyl)methyl]-; N2-(4-Methylbenzyl)-N4-(3-chlorophenyl)-5-nitropyrimidine-2,4,6-triamine; CAS 577790-39-7
EINECS	Contact for details

Quality Control

Our N⁴-(3-Chlorophenyl)-N²-(4-Methylbenzyl)-5-Nitropyrimidine-2,4,6-Triamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assay and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.