Description

Bone Sialoprotein 1 (131-137) (Mouse) is a specific peptide fragment derived from the mouse Bone Sialoprotein 1 protein, with the CAS registry number 577725-62-3. This high-purity synthetic peptide is a critical research tool for studying cell-matrix interactions, osteoblast differentiation, and bone mineralization processes. It is primarily utilized by researchers and developers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on skeletal biology, biomaterials, and therapeutic development for bone-related diseases.

Application

• Biomedical Research: Used as a key reagent in studies investigating the role of Bone Sialoprotein in osteogenesis, cell adhesion, and signaling pathways.
• Biomaterial Coating: Applied to functionalize implant surfaces (e.g., titanium, hydroxyapatite) to enhance osteointegration and bone cell attachment in vitro.
• Assay Development: Serves as a standard or coating antigen in ELISA, cell adhesion assays, and other biochemical tests to quantify protein interactions.
• Antibody Production & Validation: Used as an immunogen or a specific target for generating and characterizing polyclonal or monoclonal antibodies.
• Signal Pathway Studies: Employed to elucidate mechanisms of integrin-mediated signaling and its impact on bone formation and remodeling.
• Drug Discovery Screening: Utilized in high-throughput screening platforms to identify molecules that modulate BSP-related interactions for potential therapeutic agents.

Basic Information

Product Name	Bone Sialoprotein 1 (131-137) (Mouse)
CAS No.	577725-62-3
Molecular Formula	C34H56N10O12S
Molecular Weight	828.94 g/mol
Synonyms	BSP (131-137); BSP-1 (131-137), mouse; Bone Sialoprotein I fragment (131-137); Peptide BSP 131-137; LYS-ARG-SER-ARG-TYR-ASP-SER (KRKRYDS); Integrin-binding peptide; Osteopontin-related peptide; Cell adhesion peptide
EINECS	Contact for details

Quality Control

Our Bone Sialoprotein 1 (131-137) (Mouse) is manufactured under stringent conditions to ensure high batch-to-batch consistency and reliability for critical research. Each lot undergoes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, sequence verification, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Sequence	Lys-Arg-Lys-Arg-Tyr-Asp-Ser (KRKRYDS)
Molecular Weight	828.94 ± 1.0 Da (by MS)
Solubility	Soluble in water or aqueous buffer
Single Peak on HPLC	Present
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.