Description

2-Chloro-N-[4-(trifluoromethyl)phenyl]propanamide is a specialized organic intermediate featuring a reactive chloroacetamide group and a trifluoromethylphenyl moiety. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research and development chemists, process development scientists, and manufacturers in fine chemical and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, or insecticides, leveraging the biological activity of the trifluoromethyl group.
• Ligand and Catalyst Development: Used in organic chemistry research to create novel ligands for metal-catalyzed coupling reactions or asymmetric synthesis.
• Material Science Research: Potential monomer or modifier in the development of specialty polymers with unique surface properties or stability.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-N-[4-(trifluoromethyl)phenyl]propanamide
CAS No.	572881-42-6
Molecular Formula	C10H9ClF3NO
Molecular Weight	251.63 g/mol
Synonyms	2-Chloro-N-[4-(trifluoromethyl)phenyl]propanamide; 2-Chloro-N-(4-(trifluoromethyl)phenyl)propanamide; α-Chloro-N-(4-trifluoromethylphenyl)propionamide; Propanamide, 2-chloro-N-[4-(trifluoromethyl)phenyl]-; 572881-42-6; N-(4-Trifluoromethylphenyl)-2-chloropropionamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-[4-(trifluoromethyl)phenyl]propanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.