Description

4-[6-(6-Bromo-8-Cyclopentyl-5-Methyl-7-Oxo-7,8-Dihydro-Pyrido[2,3-D]Pyrimidin-2-Ylamino)-Pyridin-3-Yl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for research and development in drug discovery. This compound is a key synthetic building block in the development of novel kinase inhibitors and other targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) focused on oncology and inflammatory disease pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex small-molecule drug candidates targeting specific protein kinases.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Oncology Research: Serves as a core scaffold for developing potential anti-cancer therapeutics.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening (HTS) and biochemical assays.
• Custom Synthesis: A starting material for the custom synthesis of labeled (e.g., deuterated, fluorinated) or structurally modified analogs for advanced research.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and pharmacology.

Basic Information

Item	Details
Product Name	4-[6-(6-Bromo-8-Cyclopentyl-5-Methyl-7-Oxo-7,8-Dihydro-Pyrido[2,3-D]Pyrimidin-2-Ylamino)-Pyridin-3-Yl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	571188-82-4
Molecular Formula	C27H34BrN7O3
Molecular Weight	584.51 g/mol
Synonyms	4-[6-[(6-Bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[6-[(6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazine-1-carboxylate; BOC-protected pyridopyrimidine-piperazine intermediate; CAS 571188-82-4; 571188-82-4; 4-(6-((6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-[6-(6-Bromo-8-Cyclopentyl-5-Methyl-7-Oxo-7,8-Dihydro-Pyrido[2,3-D]Pyrimidin-2-Ylamino)-Pyridin-3-Yl]-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to ensure traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere. Keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.