Description

6-Bromo-8-Cyclopentyl-2-Methanesulfinyl-5-Methyl-8H-Pyrido[2,3-D]Pyrimidin-7-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of targeted kinase inhibitors. It is primarily sought by pharmaceutical companies and contract research organizations (CROs) engaged in the development of novel therapeutic agents for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent and selective kinase inhibitors for cancer therapy.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate efficacy and selectivity.
• Preclinical Drug Development: Serves as a critical precursor in the scale-up synthesis of active pharmaceutical ingredients (APIs) for toxicology and early-phase clinical studies.
• Biochemical Probe Synthesis: Utilized to create tool compounds for investigating specific biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	6-Bromo-8-Cyclopentyl-2-Methanesulfinyl-5-Methyl-8H-Pyrido[2,3-D]Pyrimidin-7-One
CAS No.	571188-81-3
Molecular Formula	C₁₇H₁₈BrN₃O₂S
Molecular Weight	408.31 g/mol
Synonyms	6-Bromo-8-cyclopentyl-2-(methylsulfinyl)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; 8-Cyclopentyl-6-bromo-2-methanesulfinyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one; 571188-81-3; Pyrido[2,3-d]pyrimidin-7-one, 6-bromo-8-cyclopentyl-2-(methylsulfinyl)-5-methyl-; 6-Bromo-8-cyclopentyl-2-(methylsulfinyl)-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Cyclopentyl-2-Methanesulfinyl-5-Methyl-8H-Pyrido[2,3-D]Pyrimidin-7-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.