Description

6-Methyl-N'-(4-(Pyridin-3-Yl)Pyrimidin-2-Yl)Benzene-1,3-Diamine is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound matters for its role as a critical building block in the synthesis of targeted small molecule therapeutics, particularly kinase inhibitors. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology industries for developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitor drug candidates for oncology and inflammatory diseases.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a reference standard or probe compound in biochemical assays to study specific biological pathways.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial chemical entities for client-specific projects.

Basic Information

Product Name	6-Methyl-N'-(4-(Pyridin-3-Yl)Pyrimidin-2-Yl)Benzene-1,3-Diamine
CAS No.	571187-03-6
Molecular Formula	C₁₆H₁₅N₅
Molecular Weight	277.33 g/mol
Synonyms	1,3-Benzenediamine, 6-methyl-N'-[4-(3-pyridinyl)-2-pyrimidinyl]-; 6-Methyl-N-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine; 2-[(3-Amino-5-methylphenyl)amino]-4-(3-pyridinyl)pyrimidine; 3-Methyl-5-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]aniline; 571187-03-6; 4-(Pyridin-3-yl)-N-(3-amino-5-methylphenyl)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 6-Methyl-N'-(4-(Pyridin-3-Yl)Pyrimidin-2-Yl)Benzene-1,3-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.