Description

1(2H)-Pyrimidinepropanoic Acid, α-Amino-3,4-Dihydro-3-Methyl-2,4-Dioxo-, (Alphas)- (9Ci) is a high-purity, non-natural amino acid derivative featuring a functionalized pyrimidine core. This compound matters as a sophisticated pharmaceutical intermediate and building block for medicinal chemistry research, enabling the synthesis of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Bioconjugation & Peptidomimetics: Serves as a specialized amino acid analog for creating modified peptides and protein conjugates with enhanced properties.
• Agrochemical Development: Intermediate in the research and synthesis of new generation herbicides and plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke chemical synthesis projects requiring high-purity, complex heterocyclic compounds.

Basic Information

Product Name	1(2H)-Pyrimidinepropanoic Acid, α-Amino-3,4-Dihydro-3-Methyl-2,4-Dioxo-, (Alphas)- (9Ci)
CAS No.	569371-09-1
Molecular Formula	C8H11N3O4
Molecular Weight	213.19 g/mol
Synonyms	(αS)-α-Amino-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinepropanoic acid; (S)-2-Amino-3-(3-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)propanoic acid; 4-[(1S)-2-Amino-1-carboxyethyl]-3-methyl-2,6-pyrimidinedione; 3-Methylisocytosine alanine derivative; NSC 760463; A pyrimidine-based non-proteinogenic amino acid; 1(2H)-Pyrimidinepropanoic acid, α-amino-3,4-dihydro-3-methyl-2,4-dioxo-, (αS)-
EINECS	Contact for details

Quality Control

Every batch of our 1(2H)-Pyrimidinepropanoic Acid derivative is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical specifications are provided with each shipment. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.