Description

n-T-Butoxycarbonyl-2-(Trifluoromethoxy)Aniline is a high-purity, protected aniline derivative featuring both a tert-butoxycarbonyl (Boc) protecting group and a trifluoromethoxy substituent. This compound is a critical pharmaceutical intermediate and advanced building block for the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability and lipophilicity imparted by the trifluoromethoxy group.
• Peptide Chemistry & Protecting Group Strategy: The Boc group serves as a temporary amine protector, enabling selective synthesis in complex multi-step reactions for peptides and other bioactive molecules.
• Material Science Research: Acts as a precursor for specialty polymers and advanced organic materials requiring specific fluorine-containing aromatic units.
• Chemical Research & Development: A versatile reagent for academic and industrial research in organic synthesis, methodology development, and library synthesis for high-throughput screening.

Basic Information

Product Name	n-T-Butoxycarbonyl-2-(Trifluoromethoxy)Aniline
CAS No.	561304-39-0
Molecular Formula	C₁₂H₁₄F₃NO₃
Molecular Weight	277.24 g/mol
Synonyms	2-(Trifluoromethoxy)aniline, N-Boc derivative; N-Boc-2-(Trifluoromethoxy)aniline; tert-Butyl [2-(trifluoromethoxy)phenyl]carbamate; N-(tert-Butoxycarbonyl)-2-(trifluoromethoxy)aniline; 2-(Trifluoromethoxy)phenylcarbamic acid tert-butyl ester; Boc-2-(Trifluoromethoxy)aniline; CAS 561304-39-0; N-Boc-2-trifluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our n-T-Butoxycarbonyl-2-(Trifluoromethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.