Description

7-(3-Chloropropoxy)-4-Chloroquinazoline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinazoline backbone. This compound is of significant commercial importance for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially kinase inhibitors.
• Oncology Research: Serves as a core scaffold for developing compounds that target specific cancer cell pathways.
• Chemical Synthesis: Used in organic chemistry research for constructing complex heterocyclic systems and exploring structure-activity relationships (SAR).
• API Development: Employed in the process development and scale-up stages for new Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and inhibition mechanisms.

Basic Information

Product Name	7-(3-Chloropropoxy)-4-Chloroquinazoline
CAS No.	557770-90-8
Molecular Formula	C11H10Cl2N2O
Molecular Weight	257.11 g/mol
Synonyms	4-Chloro-7-(3-chloropropoxy)quinazoline; 7-(3-Chloropropoxy)-4-chloro-quinazoline; 4-Chloro-7-(3-chloropropoxy)quinazoline; Quinazoline, 4-chloro-7-(3-chloropropoxy)-; 557770-90-8; 4-Chloro-7-(γ-chloropropoxy)quinazoline
EINECS	Contact for details

Quality Control

Our production of 7-(3-Chloropropoxy)-4-Chloroquinazoline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications, which typically include identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.