Description

7-(3-Hydroxy-Propoxy)-3H-Quinazolin-4-One is a high-purity, advanced pharmaceutical intermediate with a defined quinazolinone core structure. This compound is critical for the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable building block for complex molecular development. It is primarily utilized by the pharmaceutical and biotechnology industries for the research and production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinazolinone-based active pharmaceutical ingredients (APIs).
• Oncology Research: Used in the development of potential anti-cancer agents targeting specific enzymatic pathways.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for creating tyrosine kinase inhibitors and other targeted therapies.
• Chemical Biology: Employed as a probe or precursor in biochemical research to study protein-ligand interactions.
• Process Development: Used for scaling up and optimizing synthetic routes in pilot plant and commercial manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs.

Basic Information

Product Name	7-(3-Hydroxy-Propoxy)-3H-Quinazolin-4-One
CAS No.	557770-89-5
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	7-(3-Hydroxypropoxy)-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 7-(3-hydroxypropoxy)-; 7-(3-Hydroxypropoxy)quinazolin-4(3H)-one; 7-(3-Hydroxypropoxy)-3,4-dihydroquinazolin-4-one; 7-(3-Hydroxypropoxy)-4-hydroxyquinazoline; 7-(3-Hydroxypropyloxy)-3H-quinazolin-4-one; 557770-89-5 (CAS); 7-(3-Hydroxypropoxy)-4-quinazolinol
EINECS	Contact for details

Quality Control

Our 7-(3-Hydroxy-Propoxy)-3H-Quinazolin-4-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques like HPLC and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.