Description

3-Fluoro-4-Piperidin-1-Yl-Benzaldehyde is a high-purity, versatile aromatic aldehyde building block featuring a fluorine substituent and a piperidine moiety. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluoro-piperidine motif.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-4-Piperidin-1-Yl-Benzaldehyde
CAS No.	553620-09-0
Molecular Formula	C₁₂H₁₄FNO
Molecular Weight	207.25 g/mol
Synonyms	4-(Piperidin-1-yl)-3-fluorobenzaldehyde; 3-Fluoro-4-(1-piperidinyl)benzaldehyde; 3-Fluoro-4-piperidin-1-ylbenzaldehyde; Benzaldehyde, 3-fluoro-4-(1-piperidinyl)-; 3-Fluoro-4-piperidinobenzaldehyde; 1-(5-Formyl-2-fluorophenyl)piperidine; FPPB (abbreviation); 553620-09-0 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Piperidin-1-Yl-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.