Description

2,4-Difluoro-6-Iodophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents, makes it a valuable precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated and iodinated drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides where the difluoro-iodophenol moiety contributes to biological activity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for transition metal catalysis, leveraging the halogen atoms for further functionalization.
• Organic Electronic Materials: Acts as a precursor in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create biaryl structures.

Basic Information

Product Name	2,4-Difluoro-6-Iodophenol
CAS No.	551002-42-7
Molecular Formula	C6H3F2IO
Molecular Weight	271.99 g/mol
Synonyms	6-Iodo-2,4-difluorophenol; 2,4-Difluoro-6-iodo-1-hydroxybenzene; Phenol, 2,4-difluoro-6-iodo-; 2,4-Difluoro-6-iodophenol; 1-Hydroxy-2,4-difluoro-6-iodobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-6-Iodophenol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.