Description

Methyl 6-Fluoro-1-Methyl-1H-Indole-2-Carboxylate is a high-value fluorinated indole derivative, a crucial synthetic intermediate in modern organic chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific indole-based motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorinated indole structure can contribute to biological activity and metabolic stability.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and organic electronic materials.
• Chemical Biology Probe Development: Employed in creating fluorescent tags, enzyme inhibitors, or other molecular probes for biological research and diagnostic applications.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Methyl 6-Fluoro-1-Methyl-1H-Indole-2-Carboxylate
CAS No.	550349-31-0
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	Methyl 6-Fluoro-1-methylindole-2-carboxylate; 6-Fluoro-1-methyl-1H-indole-2-carboxylic acid methyl ester; 1-Methyl-6-fluoroindole-2-carboxylic acid methyl ester; 2-Carbomethoxy-6-fluoro-1-methylindole; Methyl 1-methyl-6-fluoroindole-2-carboxylate; 6-Fluoro-1-methylindole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Fluoro-1-Methyl-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Specifications are aligned with the needs of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.