Description

4,8-Dichloro-5H-Pyrimido[5,4-B]Indole CAS NO 549488-69-9 is a high-purity, heterocyclic organic compound belonging to the fused pyrimidoindole class, serving as a critical advanced pharmaceutical intermediate. Its unique molecular scaffold makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential therapeutic agents, particularly in oncology and central nervous system (CNS) drug research.
• Agrochemical Research: Used as a core structure for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Investigated as a monomer or dopant for creating specialized organic electronic materials and dyes.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Fine Chemical Synthesis: Building block for creating complex, high-value specialty chemicals used in various advanced manufacturing processes.

Basic Information

Product Name	4,8-Dichloro-5H-Pyrimido[5,4-B]Indole
CAS No.	549488-69-9
Molecular Formula	C10H5Cl2N3
Molecular Weight	238.07 g/mol
Synonyms	4,8-Dichloro-5H-pyrimido[5,4-b]indole; 5H-Pyrimido[5,4-b]indole, 4,8-dichloro-; 4,8-Dichloropyrimido[5,4-b]indole; 4,8-Dichloro-5H-pyrimido[5,4-b]indole; Pyrimido[5,4-b]indole, 4,8-dichloro-5H-; 549488-69-9 (CAS); 4,8-Dichloro-5H-pyrimido[5,4-b]indole
EINECS	Contact for details

Quality Control

Our 4,8-Dichloro-5H-Pyrimido[5,4-B]Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.